Unable to launch native app in simulator

Hi All,
i am using Appium v1.21.0 and IOS 14.5. When i try to run script, it launches Simulator and install app but fails to open installed app and throws error. Can any one please help me how to resolve this issue.

Error : Failed to create WDA session (An unknown server-side error occurred while processing the command. Original error: Could not proxy command to the remote server. Original error: connect ECONNREFUSED

Tried with different WebDriver agent port, still not successful.

Prathyush R J

Does it work with ‘Appium Inspector’?